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15 Being a powerful antioxidant, glutathione plays a critical role in several metabolic pathways: DNA and protein synthesis, amino acid transport, enzyme activation, immune system function, scavenging free radicals eg hydrogen peroxide, cofactor in Phase I cytochrome P450 enzyme-mediated detoxification, amino acid translocation across cell membranes, detoxification of xenobiotics, maintenance of sulfhydryl groups of proteins, mitochondrial function and maintenance of mitochondrial DNA, catalysis of exchange reactions and many more
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Notably, betaine can inhibit alcohol-induced increases in hepatocyte SAH (a potent inhibitor of methylation reactions), increase caspase-3 levels, and reduce DNA content, demonstrating therapeutic potential (116)
Those seeking the benefits of glutathione supplementation for immune health and vitality would often need to take higher doses of complicated
